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The Fatty Acid Synthase Inhibitor Orlistat Reduces Experimental Metastases And Angiogenesis In B16-F10 Melanomas.
Br J Cancer. 2012 Sep 4;107(6):977-87. doi: 10.1038/bjc.2012.355. Epub 2012 Aug 14. Seguin F, Carvalho MA, Bastos DC, Agostini M, Zecchin KG, Alvarez-Flores MP, Chudzinski-Tavassi AM, Coletta RD, Graner E. Abstract BACKGROUND: Fatty acid synthase (FASN) is overexpressed and associated with poor ...
Patologia Bucal
Artigo, 10 anos
Fatty Acid Synthase Inhibition With Orlistat Promotes Apoptosis And Reduces Cell Growth And Lymph Node Metastasis In a Mouse Melanoma Model.
Int J Cancer. 2008 Dec 1;123(11):2557-65. doi: 10.1002/ijc.23835. Carvalho MA, Zecchin KG, Seguin F, Bastos DC, Agostini M, Rangel AL, Veiga SS, Raposo HF, Oliveira HC, Loda M, Coletta RD, Graner E. Abstract Fatty acid synthase (FASN) is the enzyme responsible for the endogenous synthesis of the ...
Patologia Bucal
Artigo, 10 anos